Are itch and scratching the nausea and vomiting of skin?
Identifieur interne : 000E32 ( Main/Exploration ); précédent : 000E31; suivant : 000E33Are itch and scratching the nausea and vomiting of skin?
Auteurs : Sattar Ostadhadi [Iran] ; Ehsan Azimi [États-Unis] ; Ethan A. Lerner [États-Unis] ; Ahmad-Reza Dehpour [Iran]Source :
- Experimental Dermatology [ 0906-6705 ] ; 2016-05.
Abstract
The physiologic similarities between itch and nausea may not be evident initially, but they share the role of repelling irritants and toxins from the body by inducting scratching and vomiting, respectively. In addition, itch and nausea frequently occur together in certain conditions such as uraemia. Here we show that the mechanisms underlying itch and nausea overlap and that advances in either field may influence the identification of novel drug targets, particularly for itch.
Url:
DOI: 10.1111/exd.12935
Affiliations:
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<front><div type="abstract">The physiologic similarities between itch and nausea may not be evident initially, but they share the role of repelling irritants and toxins from the body by inducting scratching and vomiting, respectively. In addition, itch and nausea frequently occur together in certain conditions such as uraemia. Here we show that the mechanisms underlying itch and nausea overlap and that advances in either field may influence the identification of novel drug targets, particularly for itch.</div>
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